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Post Doc Instructions:
Please do not submit an application to this posting. To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”.
Department Name/Job Location:
This position is in the Department of Orthopaedic Surgery. This position is for the Medical School Campus.
The Orthopaedic Research Laboratories (PI: Dr. Audrey McAlinden; Co-Investigator, Dr. Farshid Guilak) in the Department of Orthopaedic Surgery at Washington University in Saint Louis, has an opening for a post-doctoral research associate. The post-doc will work on an NIH-funded study to investigate the function and mechanism of specific long non-coding RNAs in regulating stem/progenitor cell differentiation toward the chondrocyte lineage. The long-term goals of these studies are to determine new mechanisms and/or identify novel targets that can be exploited for future approaches to engineer new cartilage tissue or ameliorate cartilage breakdown resulting from conditions such as joint trauma and osteoarthritis.
Ph.D. degree in the field of molecular/cellular biology, biochemistry or a closely-related field.
Strong background in a range of molecular biology and RNA-based approaches (e.g. cloning and construct design, shRNA techniques, RNA pulldown assays, FISH, RNA-Seq analysis).
Previous experience working with primary stem/progenitor cells and differentiation assays.
Base pay commensurate with experience.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Whether suffering from a sports injury, hip pain, back pain or any musculoskeletal condition, Washington University Orthopedics provides a full complement of comprehensive orthopedic services to meet the needs of every patient. Combining the best in both inpatient treatment and outpatient care and rehabilitation, the practice is nationally recognized for outstanding orthopedic care, innovative research and advanced professional training. It is ranked among the best orthopedic practices and holds the distinction of being listed on the Honor Roll by U.S. News & World Report. The practice is considered an innovator in both conservative orthopedic care and minimally invasive microsurgical techniques. Affiliated with Barnes-Jewish Hospital and St. Louis Children’s Hospital, Washington University Orthopedics has the unique ability to offer inpatient treatment for the most challenging cases within a top-tier academic medical center as well as outpatient surgery and care across the St. Louis region in Chesterfield, Town & Country, South County and the Central West End. The practice offers expertise in ten orthopedic subspecialties – foot and ankle, hand and wrist, hip and knee, cancer, pediatric and adolescent orthopedics, physical medicine and rehabilitation (physiatry), shoulder and elbow, spine (including scoliosis), sports medicine and fracture care/trauma. The orthopedic specialists are dedicated to providing safe, compassionate and family-centered care for both simple and complex orthopedic conditions. Because of the skill and experience of the doctors and staff, it is the official medical provider for the St. Louis Blues hockey team, Washington University varsity athletics and several local school athletic teams. Washington University Orthopedics brings world-class care to patients from all ages and walks of life in St. Louis and the surrounding communities.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Some experience in musculoskeletal research would be an advantage.
Knowledge of other specialized techniques, such as ChIRP-Seq, proteomics and CRISPR technology is advantageous.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.