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Post Doc Instructions:
Please do not submit an application to this posting.� To apply for this postdoctoral research opportunity, follow the directions below in �Applicant Special Instructions�.
Department Name/Job Location:
This position is in the Department of Orthopaedic Surgery. This position is for the Medical School Campus.
This position seeks to elucidate the cellular and molecular mechanisms of inflammatory osteolysis and metabolic regulation of skeletal/joint homeostasis and pathology. The approaches include the development and use of genetically engineered mice as disease models of inflammatory bone lysis and joint diseases to mimic human bone and joint pathologies.
The candidate will work closely with the principal investigator to outline research goals, review relevant literature, design research protocols independently based on methods in the literature related to research project, including developing procedures for the data collection, verification and management of project. The candidate will also present data at meetings, and assists with grant preparation and publication of results. The candidate will participate in routine daily functions of the laboratory as a team player.
Doctorate degree (M.D. and/or Ph.D.) with basic experience in research lab operations and relevant training in cell and molecular biology, preferably related to immunology, inflammation and bone.
Highly motivated, organized, reliable, and career-driven.
Demonstrated ability to perform well in a research laboratory setting, to work independently and communicate effectively.
Ability to maintain complete and organized records.
Working knowledge of standard computer software and general lab equipment.
Excellent skills in cell cultures.
Basic knowledge on mouse genetics.
Ability to handle mice.
Strong molecular biology skills (cloning, mutagenesis, transcriptional analysis, perform mouse genotyping, isolation of mRNA and analysis, plasmid and retrovirus preparation and gene transfer) and protein analyses (Western blot, FACS, IHC/IF and ELISA).
Advanced protein chemistry and molecular biology, microscopy, and flow cytometry.
Computer literacy, including the ability to use a variety of software packages to analyze data.
Base pay commensurate with experience.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Whether suffering from a sports injury, hip pain, back pain or any musculoskeletal condition, Washington University Orthopedics provides a full complement of comprehensive orthopedic services to meet the needs of every patient. Combining the best in both inpatient treatment and outpatient care and rehabilitation, the practice is nationally recognized for outstanding orthopedic care, innovative research and advanced professional training. It is ranked among the best orthopedic practices and holds the distinction of being listed on the Honor Roll by U.S. News & World Report. The practice is considered an innovator in both conservative orthopedic care and minimally invasive microsurgical techniques. Affiliated with Barnes-Jewish Hospital and St. Louis Children’s Hospital, Washington University Orthopedics has the unique ability to offer inpatient treatment for the most challenging cases within a top-tier academic medical center as well as outpatient surgery and care across the St. Louis region in Chesterfield, Town & Country, South County and the Central West End. The practice offers expertise in ten orthopedic subspecialties – foot and ankle, hand and wrist, hip and knee, cancer, pediatric and adolescent orthopedics, physical medicine and rehabilitation (physiatry), shoulder and elbow, spine (including scoliosis), sports medicine and fracture care/trauma. The orthopedic specialists are dedicated to providing safe, compassionate and family-centered care for both simple and complex orthopedic conditions. Because of the skill and experience of the doctors and staff, it is the official medical provider for the St. Louis Blues hockey team, Washington University varsity athletics and several local school athletic teams. Washington University Orthopedics brings world-class care to patients from all ages and walks of life in St. Louis and the surrounding communities.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.