Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
This position is full-time and works approximately 40 hours per week.
Department Name/Job Location:
This position is in the Department of Orthopaedic Surgery. This position is for the Medical School Campus.
The focus of my laboratory is on the metabolism of tumors and the development of therapeutics through an understanding of the underlying biology of cancer.
Tumor metabolism is a rapidly advancing field that represents an opportunity for novel, targeted, and less toxic treatments. Specifically, lactate metabolism has emerged as central in tumorigenesis, and more recently lactate transport emerged as a targetable pathway in the treatment of cancer. Our lab is interested in the tumor microenvironment and how this may be altered to target tumor cells.
The current specific interests of the laboratory involve studies of cancers, including osteosarcoma, and the role of monocarboxylate transporters (MCTs) in tumorigenesis. We make use of cell cultures, animal models, and use of primary tissue. Interestingly, the phenotype that many cancer cells exhibit in their native microenvironment is similar to that of the intervertebral disc (IVD). Many cancer cells and IVD cells rely heavily on MCTs for survival, and undergo degeneration when those are inhibited. Our lab has an interest in how targeting MCTs effects degeneration of the IVD. This has implications for cancer metabolism as well as many spinal pathologies.
Those with basic laboratory experience are encouraged to apply.
Background in biology, biochemistry, microbiology, molecular biology or a related field.
Willingness to handle mice and perform small animal procedures.
Ability to communicate effectively and work well with others.
Ability to troubleshoot experiments and work independently.
Excellent record keeping and organizational skills.
Base pay commensurate with experience.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Whether suffering from a sports injury, hip pain, back pain or any musculoskeletal condition, Washington University Orthopedics provides a full complement of comprehensive orthopedic services to meet the needs of every patient. Combining the best in both inpatient treatment and outpatient care and rehabilitation, the practice is nationally recognized for outstanding orthopedic care, innovative research and advanced professional training. It is ranked among the best orthopedic practices and holds the distinction of being listed on the Honor Roll by U.S. News & World Report. The practice is considered an innovator in both conservative orthopedic care and minimally invasive microsurgical techniques. Affiliated with Barnes-Jewish Hospital and St. Louis Children’s Hospital, Washington University Orthopedics has the unique ability to offer inpatient treatment for the most challenging cases within a top-tier academic medical center as well as outpatient surgery and care across the St. Louis region in Chesterfield, Town & Country, South County and the Central West End. The practice offers expertise in ten orthopedic subspecialties – foot and ankle, hand and wrist, hip and knee, cancer, pediatric and adolescent orthopedics, physical medicine and rehabilitation (physiatry), shoulder and elbow, spine (including scoliosis), sports medicine and fracture care/trauma. The orthopedic specialists are dedicated to providing safe, compassionate and family-centered care for both simple and complex orthopedic conditions. Because of the skill and experience of the doctors and staff, it is the official medical provider for the St. Louis Blues hockey team, Washington University varsity athletics and several local school athletic teams. Washington University Orthopedics brings world-class care to patients from all ages and walks of life in St. Louis and the surrounding communities.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.