Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
This position is in the Department of Internal Medicine, Division of Bone and Mineral Diseases. This position is located in the BJC Institute of Health on the Medical School Campus.
The Division of Bone and Mineral Diseases at the Washington University School of Medicine is part of a dynamic multidisciplinary community of researchers dedicated to the study of local and systemic diseases affecting bone metabolism. In early 2012, the Division moved to a new space in the BJCIH as part of a Center for Musculoskeletal Research, a vibrant community of ~15 labs with complementary interests and expertise, providing a rich training environment. In addition to high-quality research facilities, career and professional development training for postdoctoral researchers at Washington University is provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups. Additional information on being a postdoc at Washington University in St. Louis can be found at postdoc.wustl.edu/prospective-postdocs.
1. The research interest of this lab is to elucidate the cellular and molecular mechanisms underlying pathological bone loss. Major ongoing projects include the study of mitochondrial dynamics in bone cells (osteoblasts and osteoclasts), and mechanisms of host-pathogen interactions in osteomyelitis. The approaches include the use of genetically engineered mice and pathogenic bacterial strains, histological and structural analyses (such as with microCT), confocal microscopy, mechanical testing, and culture of primary murine and human cells.
2. In concert with the principal investigator, the candidate is expected to design experiments with appropriate controls and execute research protocols based on methods in the literature. The candidate is expected to work towards independence in the design and execution of research projects.
3. The candidate is expected to analyze results and present data at lab meetings. Participation in preparation of publications and grant proposals is also expected.
4. The postdoctoral researcher will have the opportunity to work directly with collaborators, initiate new collaborative relationships, establish mentoring relationships, and develop an independent project. Acquisition of technical skills new to the fellow and/or laboratory is highly encouraged to improve career development.
Excellent skills in cell culture and molecular biology, mouse genotyping, plasmid and retrovirus preparation and gene transfer, and protein analysis (Western blot, FACS, IHC/IF and ELISA).
Previous microbiology experience, especially with bacterial culture and genetic manipulation as well as experience with whole animal imaging approaches, such as bioluminescence imaging or microCT.
Experience with histology, including immunostaining and confocal microscopy, and/or with analysis of mitochondria/cell metabolism.
Strong written and oral communication skills, including a demonstrated ability to publish research results as peer-reviewed journal articles.
Demonstrated computer literacy, including the ability to use a variety of software packages to store, analyze and present data (Excel, Word, PowerPoint, etc.).
Highly-motivated, eager, quick to learn, careful, organized, and reliable.
Ability to work independently and communicate with laboratory staff and collaborating investigators.
Doctoral level degree (Ph.D., M.D., Pharm.D. or equivalent).
Base pay commensurate with experience.
Post Doc Instructions:
Please do not submit an application to this posting.� To apply for this postdoctoral research opportunity, follow the directions below in �Applicant Special Instructions�.
Applicant Special Instructions:
To apply for this position, please send a cover letter and C.V. to:
This position works in a laboratory environment with potential exposure to biological, chemical and radioactive hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
Internal Applicant Instruction:
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.