Career Center

The focus of Dr. Feeley and Dr. Liu’s lab at UCSF/SFVA is to understand how stem cells interact and differentiate during muscle regeneration.  We run a highly productive and creative translational lab within the UCSF Department of Orthopedic Surgery.  We focus on clinically relevant models of injury and repair, particularly rotator cuff injuries.  We are collaborating with Dr. Kevin Healy at UC-Berkeley to develop a novel matrix-assisted promyogenic fibro/adipogenic progenitor (FAP) stem cells transplantation therapy in treating rotator cuff tears. More information on this and other projects can be found at https://feeleylab.ucsf.edu/

We are currently seeking a talented and hard-working postdoctoral research scholar to study the mechanism of function of beige fat-like FAPs in rotator cuff muscle after injury.   The essential functions of the applicant would include (but are not limited to):

• Isolates stem cells from human and mouse muscle tissue with FACS
• Performs transcriptional analysis of muscle stem cells (including RT-PCR, bulk and single cell RNA sequencing (scRNAseq)
• Performs muscle stem cell culture and differentiation assays
• Performs matrix assisted muscle stem cell culture and differentiation assays
• Performs mouse rotator cuff surgeries
• Performs inducible tissue-specific knock-in/knock-out mice strain generation and maintenance.
• Performs mouse shoulder function analysis.
• Performs tissue sectioning and histology analysis.
• Prepares manuscripts with the direction and assistance of the P.I.
• Performs all duties in compliance with safety regulations; maintains working knowledge of hazardous substances used in the laboratory, antidotes and safe handling methods; disposes of hazardous materials in accordance with regulations

The successful candidate should possess a Doctorate degree (MD, PhD, VMD, or DDS) in area directly related to field of research specialization. Hands-on experience with RNA/protein extraction, RT-PCR, Western-blot, cell culture, tissue sectioning/staining are required. Previous experience with mouse surgeries, FACS, scRNA-sequencing, hydrogel synthesis and modification, stem cell differentiation are highly recommended.

We provide on a collaborative, supportive environment that upholds the goals of promoting diverse and equitable scientific research.

If you are interested in joining our lab, please email your resume to liu.xuhui@ucsf.edu