Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
This opportunity is full-time and works approximately 40 hours per week. Hours are generally normal business hours but may vary due to the timing for experiments and other research activity deadlines.
The interest of this lab is investigation of skeletal and joint diseases that occur in response to local or systemic inflammation, developing mouse models of bone diseases, and investigating signal transduction pathways in macrophages, osteoclasts, and osteoblasts.
The primary focus of the work includes but is not limited to the following:
1) Isolation of monocytes/macrophages and osteoblasts. Performing tissue culture and differentiation studies. Studies signal transduction and performing molecular and biochemical assays.
2) Hands on work with mice is required: the ability to handle and monitor mice, perform injections, harvest tissue and perform breeding and screening.
3) Collecting, organizing, and disseminating data.
Department Name/Job Location:
This opportunity is in the Department of Orthopedic Surgery-Research and located at IOH (11th floor) on the Medical School Campus.
Candidates with extensive prior experience in cell, molecular biology or related fields with at least a Bachelor’s degree are encouraged to apply.
Must have troubleshooting skills, independent analytical thinking, and research planning skills. Demonstrated ability to work independently and communicate with laboratory staff and investigators. Ability to maintain complete and organized records/reports. Working knowledge of computer software and general lab equipment.
Advanced skills and experience with tissue cell culture techniques
Advanced molecular biology skills
Experience with microscopy
Proficiency in basic molecular biology techniques including DNA, RNA, Protein isolation and purification; PCR, reverse transcription PCR, Immunoblot, ELISA.
Experience with immunocyto- and histo-chemistry; experience working with frozen and paraffin embedded tissue. Proficiency in these techniques is a plus.
Experience with flow cytometry and immunology is a plus.
Working knowledge of Excel, Photoshop. Knowledge of Image J is a plus.
The hiring range for this position is commensurate with experience.
The Department of Orthopedic Surgery/Research at the Washington University School of Medicine is ranked number 1 in federal funding among Ortho department in the US. It is considered one of the leading academic training programs, dedicated to the study of musculoskeletal diseases. The balance of outstanding faculty, State-of-the-Art facilities, and leading research edge ensure excellence across the missions of maintaining national prominence in research, teaching and patient care.
This opportunity is eligible for full-time benefits. Please visit our website at http://hr.wustl.edu to view a summary of benefits.
Internal Applicant Instruction:
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Applicant Special Instructions:
Works in laboratory environment with potential exposure to biological, chemical and radioactive hazards. Must be physically able to wear protective equipment. Must be able to provide standard care to research animals.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplin...ary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.