Successful candidates will work with a team of researchers at The Carroll Laboratories in the Department of Orthopedic Surgery at Columbia University Medical Center at NewYork-Presbyterian Hospital in New York, NY. One project focuses on role of inflammation in disc degeneration, with an emphasis on inflammatory signaling and mechanobiology. This position requires expertise in biomedical engineering, cell biology, immunology, and/or biochemistry. Candidates should be highly motivated and independent, with expertise in musculoskeletal biology and/or bioengineering, in vivo experiments using rat and mouse models, biomechanics, and molecular biology. Previous experience in mouse models, breeding, and immunohistochemistry is desired.
The second project focuses on multiscale biomechanics and mechanobiology of disc degeneration and requires expertise in cellular and molecular bioengineering and multiscale biomechanics. Candidates should have a demonstrated record of academic and research achievement, as well as excellent written and verbal communication skills to work with a multidisciplinary research team.
Candidates with a MD, PhD or MD/PhD degrees (or equivalent) are invited to submit their application.
Current research projects are funded by the NIH. Applicants must have completed their degree requirements.
Proj. 1. Experience in musculoskeletal biology and biomechanics, in vivo experiments using mouse/rodent models, and molecular biology.
Proj. 2. Applicants must have experience in musculoskeletal biomechanics, image analysis, microscopy and molecular biology. Experience with finite element modeling is preferred, as well as in vivo animal model.
Internal Number: Job Req. No. 0007668
About Columbia University Medical Center
The Department of Orthopedic Surgery at NewYork-Presbyterian's Columbia University Medical Center is committed to providing world-class training to the next generation of orthopedic surgeons — and the opportunity for you to become involved in groundbreaking research. Led by William N. Levine, MD, Chairman, our physician-scientists are in the vanguard of developing new and better treatments for musculoskeletal disease, and improving quality of life for all patients.
The Chahine Lab:
Our research focuses on degeneration and regeneration of musculoskeletal soft tissues, primarily the intervertebral disc in the spine. Using tools of bioengineering, we study the biomechanics and mechanobiology of cells and tissues, with emphasis on degradation processes and inflammation. We also collaborate with physicians in the departments of Orthopedic Surgery and Rehabilitation Medicine, to develop biomarkers of intervertebral disc disorders and back pain.
We are grateful for the funding support from the National Institutes of Health (NIH), the National Science Foundation (NSF), New York State Department of Health (ECRIP program), and the American Orthopedic Society for Sports Medicine (AOSSM).