TECHNICAL ASSOCIATE I, Biological Engineering, to join the team of Prof. Alan Grodzinsky and Dr. Murat Cirit. Responsibilities include culture of human explant tissue (cartilage, bone, synovium), preparing culture media, wet-bench laboratory work (ELISAs, MSD, IHC, etc.), data analysis and presentation, preparing weekly progress reports, data/experimental results/updates, planning for following week and any long-term issues that need addressing, and documenting protocols and experimental details.
The Tissue Chips in Space program, supported by the Center for the Advancement of Science in Space and National Institutes of Health-National Center for Advancing Translational Sciences, will focus on human physiology and disease onboard the International Space Station U.S. National Laboratory. Data from this translational research--which will feature tissue chips (or organs-on-chips)--will help scientists develop and advance novel technologies benefiting human health on Earth and in space.
The MIT research focuses on a cartilage-bone-synovium joint tissue chip model studying the effects of space flight on musculoskeletal disease biology, motivated by post-traumatic osteoarthritis and bone loss. The effects of pharmacological agents to ameliorate bone and cartilage degeneration will be tested on Earth and in the International Space Station using a quantitative, high-content experimental and computational approach.
REQUIRED: B.S./B.A. in bioengineering, biology, or related discipline; minimum of two years' relevant laboratory experience; experience with basic biology lab techniques (aseptic technique, human/mammalian cell culture, biochemical assays); excellent written and verbal communication skills; ability to follow complex instructions, multitask, meet deadlines, and work independently and as part of a team; solid organizational and planning skills; self-motivation; detail-orientation; and proficiency with Word, Excel, and PowerPoint. Experience with explant and primary cell culture preferred. Job #15029
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